As the U.S. Centers for Disease Control and Prevention (CDC) has said: “Accurate, accessible and actionable communication is foundational to patient understanding and decisions – and ultimately to prevention and better outcomes.”
That’s exactly what UPL aims to deliver.
From toolkit to transformation
What began as a set of communications principles has evolved into an enterprise-wide capability and a driver of meaningful change. Supported by our Global Purpose & Patient Experience team (GP&PE), UPL is now integrated across the entire organization. It’s also backed by a growing community of internal champions within ww5 and a comprehensive set of shared tools, including our AI-assisted writing guide and a Cultural Adaptation Toolkit.
This transformation, embedding UPL into everything we do, allows us to drive our efforts to put health in every hand by driving understanding for every patient, no matter who they are, where they live or what they have. UPL, at its core, is anchored to our fundamental belief that every person deserves the opportunity to live a healthy, fulfilling life.
A patient-centered collaboration in action
As UPL continues to evolve, we have been engaging directly with patients to help us test what works, uncover what’s missing and bring clarity into the moments that matter most.
One recent illustration of these collaborations comes from the UPL program’s work with our Patient Engagement & Recruitment (PER) team. Together, they reimagined the core recruitment materials for a recent clinical trial — including the outreach letter, study brochure and visit guide — with a focus on women living with triple-negative breast cancer.
Using UPL principles, these materials were transformed to be clearer, more culturally responsive and emotionally resonant — ensuring the tone, visuals and message would feel personal and empowering.
What patients told us
After the content was revised, it was brought back to patients to gather feedback and understand how the changes landed. They were asked whether they felt more informed, confident and respected and their voices affirmed the shift which shaped our path forward.
Direct patient feedback showed consistent improvement across three dimensions: understanding, confidence and trust. One patient, Atiba, summed it up powerfully:
“I see the thoughtfulness and keeping the ‘human part’ in the conversation. The first review, I could tell people with a scientific background wrote it, but in the second review, I could tell you were talking to me."
Others shared how important it was to see themselves reflected in the imagery and tone. Carol noted:
“Everything in that moment is already a whirlwind. Bring it in, make it concise, make it understandable. This is the first step to healing.”
Even across a small sample of interviews, the impact was clear: patients felt more informed, more respected and ready to act.
Where we’re headed next
Looking to the future, ww5 plans to invest in tools and teams that help patients understand what’s possible. Because when people understand their choices, they can take part in them. When language includes them, it empowers them.